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New study indicates that people with high level of Omega-3 have lower risk of premature death.
New study was published in Nature Communications magazine that explores the link between Omega-3 index and risk of death for any reason. It shows that people with higher levels of Omega-3 EPA and DHA in blood (i.e. Omega-3 index) live longer lives than people with lower levels of Omega-3. In other words, people, who passed away with relatively low levels of Omega-3 died prematurely, meaning, with all others being equal, they could have lived longer if their levels of Omega-3 were higher.
In Japan, Omega-3 intake and its level in blood higher than in other countries, and they live longer than people of other countries. High index of Omega-3 is part of the reason of their longevity.
In this new paper, written by FORCE Consortium – Fatty Acids & Outcomes Research – Consortium. FORCE consists of researchers from around the world who collected data about fatty acid levels from large groups of subjects and observed them during long period of time to document what kind of diseases they develop during their lifetime. In the end that data is consolidated to get a possibly clearer picture unlike what can be produced from only one focus group. Current research was concentrated on Omega-3 levels and risk of death during follow-up period and it`s the biggest study to do that until now.
In particular, this study consists of consolidated data from 17 different groups from across the world that include 42 466, which were observed for average of 16 years, during that time passed away 15 720 people. When researchers from FORCE studied risks of death from various causes, people with highest levels of EPA + DHA had statistically significant, 13% lower risk of death than people with low levels of EPA+DHA in blood plasma. When they examined three leading causes of death – cardiovascular diseases, cancer and all other causes put together – they found statistically significant lowering of risk (comparing high and low levels of EPA+DHA in blood again) at a rate of 15%, 11% and 13% respectively.
Range between 10thand 90thpercentiles for EPA+DHA consisted of (considering levels of Omega-3 in red blood cells, i.e. Omega-3 index) from 3,5% to 7,6%. According to other studies, optimal index of Omega-3 clocks in at 8% or higher.
In the new study authors noted how this results indicate that fatty acids Omega-3 can positively affect general health and in that way slow down aging process and that they are not only helpful against heart conditions.
«Since all of these analyses were statistically adjusted for multiple personal and medical factors (i.e., age, sex, weight, smoking, diabetes, blood pressure, etc., plus blood omega-6 fatty acid levels), we believe that these are the strongest data published to date supporting the view that over the long-term, having higher blood omega-3 levels can help maintain better overall health,»said Dr. Bill Harris, who founded Fatty Acid Research Institute (FARI) and lead author of this study.
Doctor Harris was one of the inventors of Omega-3 index 17 years ago as a objective indicator of status of Omega-3 inside human body. Measurement of Omega-3 inside red blood cell membranes gives complete picture of Omega-3 ingestion during last 4 to 6 months. Today, index Omega-3 was employed in more than 200 researches.
«This comprehensive look at observational studies of circulating omega-3 fatty acids indicates that the long chain omega-3s EPA, DPA, and DHA, usually obtained from seafood, are strongly associated with all-cause mortality, while levels of the plant omega-3 alpha-linolenic acid (ALA) are less so»said Tom Brenna, PhD. and Professor of Pediatrics, Human Nutrition and Chemistry from Dell Medical School of the Universety of Texas at Austin.